Hormone Replacement Therapy(HRT)-AZABU SKIN CLINIC,Tokyo,Japan

AM10:00-PM7:00(Wednesday AM11:00-PM8:00 )
Clinic Free dial 0120-005-327
medical Spa Free dial 0120-890-992

Hormone Replacement Therapy(HRT)
Bio-identical HRT(BHRT)

Hormone Replacement Therapy(HRT)(BHRT)

Having the correct levels and ratios of hormones in your body ensures that juvenescence and health are optimized and maintained. Unfortunately, hormone production declines naturally with age. However, it is now possible to reduce the effects of aging and disease by actively increasing hormones to youthful levels with Hormone Replacement Therapy (HRT). HRT enables you to maintain not only your health and beauty but also your appearance. A combination of oral medication, injections and topical medication helps restore youthfulness Ephysically, mentally and functionally.

Various symptoms when hormone declines

・Weak muscle
・Easy to gain weight
·Loss of sexual desire
·Pain in joints
·Flabby skin
·Cold hands
·Thinning hair
·Weak nails

·Predisposition to colds or stubborn colds
·Low on energy
·Memory loss problem
·Pain during sexual intercourse
·Face burn problem
·Hair growing problems
·Worsen a condition of hair
·Sudden perspiration
·Urinary leakage
·Predisposition to constipation

Mechanism of aging

Having the correct levels and ratios of hormones in your body ensures that juvenescence and health are optimized and maintained. Unfortunately, hormone production declines naturally with age. As you can see the graph below , hormone production of 20’s gradually begins to decline, and in 40’s and early 50’s, it declines rapidly. Irregular lifestyle and dietary habit, such as lack of exercise, stress, extreme fatigue and sleep deprivation makes more declination of hormone production.

Features of our clinic

Before and after HRT, our patients are able to take the following examinations upon request.

Blood examination (liver function, kidney function, tumor marker, hormone level)
Urine test

Flow of HRT treatment


(Consultation with our Doctor) - whole day available
(Blood examination) (Urine test )
<available between 10 AM E12 AM>


(Treatment consent Esign the treatment consent form) Treatment will begin as soon as the patient agrees with our treatment program
(Various medical examinations)


(Start treatment<Start dispensing medication>)
Based on the examination, individualized hormone medication will be prescribed.


Blood examination is required once a month until hormone levels have stabilized. Thereafter, only bi-annual examinations are required.
(Blood Examination)

We offer a variety of examinations based on individual needs, such as blood examination and PET.

To patients coming from afar, we ask you to come to the clinic on your first visit, but from the second consultation on, a telephone consultation is possible, so that you can continue your hormone replacement therapy.

Types and function of Hormones


Estrogen is one of the female hormones and called estradiol, estrone, estriol. By replenishing estrogen (estrogenic hormone), it helps improve cognition, mental instability, menopausal syndrome such as insomnia, skin conditions, heart disease, stroke, Alzheimer, dryness and atrophia of vagina , and osteoporosis prevention.

Positive effect

· Improvement of cognition
· Improvement of Mental instability, menopausal syndrome such as insomnia
· Improvement of skin condition
· Heart disease prevention
· Stroke prevention
· Alzheimer prevention
· Improvement of genitourinary atrophia
· Dryness and atrophia of vagina
· Osteoporosis prevention


Progesterone is one of the female hormones which is secreted by the ovary. This hormone is essential for pregnancy, and helps relieve premenstrual syndrome (PMS), swelling and headache caused by period. It is effective for controlling symptoms of uterine bleeding by estrogen, enhancing effectiveness of estrogen by balancing withProgesterone. It also helps reducing risk of osteoporosis, heart disease, uterus cancer, breast cancer and migraine as well as improving menopausal syndrome, sexual desire and lowering percentage of body fat. It might induce sleepiness as a side-effect.

Positive effect

·Enhancing effectiveness of estrogen by balancing with Progesterone
·Reduce the risk of Osteoporosis, heart disease, uterus cancer and breast cancer ·Improvement of menopausal syndrome
·Reduce migraine
·Improvement of sexual desire
・Reduce percentage of body fat

DHEA( Dehydroepiandrosterone)

DHEA is a steroid hormone which exists the most in the body and produced by brain and adrenal cortex. DHEA is changed to testosterone, estrogen and progesterone in the body and they are a precursor substance of sex hormone. It helps prevent obesity, diabetes and heart disease. It also involves in weight loss, muscular strengthening as well as improvement of memory skill, cognition, knowledge and sexual desire.

Positive effect

·Increase in energy and realization of health
·Heart disease and cancer prevention
·Reduce cholesterol and percentage of body fat
·Improvement of memory skill and cognition
·Enhancement of immune system
·Improvement of sexual desire

HGH (Human-growth hormone)

Chemical suffix: Somatotropin HGH is produced in the pituitary gland and absorbed into the liver by the blood stream, and converted to various growth factors. HGH adjusts the metabolism of protein, electrolyte and carbohydrates, and controls fat combustion. It is secreted during the hours of sleep and affected by exercise, stress, emotion and a crash diet. This hormone controls recovery and the growth of tissues.

Benefits of Human Growth Hormone

Benefits of Human Growth Hormone

HGH is available as a prescription drug that is administered by injection. HGH is an
approved treatment for adult GH
deficiency. Adults with proven GH
deficiencies benefit from GH injections.
They enjoy stronger bone density,
increased muscle mass, improved exercise capacity, neuro-protection, and a reduced risk of future heart disease. HGH also promotes fatty acid oxidation which results to slimming and lowers cholesterol and total glyceride levels. Adults who are GH deficient also get larger muscles, more energy, and improved physical strength from replacement therapy.

Positive effect

· Improvement of nerve function, cardiopulmonary function and liver function
· Osteoporosis prevention
· Improvement of immune system and curative powers
· Reduce cholesterol level
· Reduce percentage of body fat
· Improvement of skin condition
· Increase in basal body temperature
· Recovery of sexual desire
Benefits of Human Growth Hormone


Testosterone is a major male hormone. It is secreted by the testis and adrenal gland. It helps maintain sexual desire and energy as well as restore a mental balance. When the testosterone declines, it causes various symptoms such as deficient in virility, declining of bone and muscle, increasing percentage of body fat, depression, male erectile disorder, high-blood pressure, cardiac disease, menopausal symptoms(andropause). For women, it helps to improve sexual desire, skin condition, bone density and skins elasticity.

Kinds of Testosterone

Bioidentical Testosterone Cream / Gel

Creams and gels are one of the most popular ways to administer testosterone. It is applied to the skin and is very easy to use
without the need to physically come to the clinic weekly or often.
The benefits of using gels or creams are:

  • Lesser side effect than synthetic hormones
  • Promotes a stable blood level
  • Through absorption through the skin, testosterone levels mimic the body's own production
Testosterone Shots (Injection)

Testosterone injection is another commonly prescribed
treatment for low testosterone. This is because of its ability to provide predictable and stable levels of blood testosterone.
The advantages of using injection are:

  • Directly enters the bloodstream, minimizing absorption loss
  • No possibility of metastasis to other parts
  • Provides a stable and predictable level of testosterone

Positive effect

· Improvement of menopausal symptoms
· Improvement of sexual desire
· Improvement of thinking power and memory skill
· Heart disease and Alzheimer prevention
· Reduce percentage of body fat
· Improvement of muscle strength and bone density

· Improvement of sexual desire
· Improvement of skin condition
· Improvement of bone density
· Skins elasticity


Thyroid is secreted by the thyroid gland, and involved in the development of organs and metabolism. When Thyroid declines, it causes hypothyroid, fatigue, chill, weight gain, constipation and low cognition.

Positive effect

· Improvement of skin condition and wrinkles
· Improvement of hair condition
· Improvement of poor circulation
· Strengthen nails
· Increase in basal metabolic rate
· Improvement of immune system
· Improvement of cognition

The report shown below is a sample result as a reference from the laboratory. It is revealing how closely they test submitted samples to provide the clients with detailed numbers on various categories.

Consultation (First time)   ¥5,000
<Blood examination>

Tests to perceive your hormone movement by time and more sensitive physiological movement in your body
<Multi Subject Salivary Test>
<Stress Hormone Salivary Test>

Tests to perceive neurotransmitter such as Adrenaline, Serotonin and GABA
<Neurotransmitter Urinary Test>

Valid until the end of June.
*All prices are tax exclusive.

The Medical Team


Dr. Kawashima furthers her knowledge through attending and constantly engaging in both domestic and international conferences, especially those held by the American Academy of Dermatology (AAD), the American Society for Laser Medicine and Surgery (ASLMS), and the American Academy of Anti-Aging Medicine (A4M).

Current Position:Owner and President - Azabu Skin Clinic(2002 - Present)

Associations and Affiliations:

· Associate of American Society for Laser Medicine & Surgery, Inc. (ASLMS)
· Member of the American Academy of Anti-Aging Medicine (A4M)
· Member of the Japanese Dermatology Association
· Member of the Society of Aesthetic Dermatology
· Member of the Japanese Cosmetic Science Society
· Member of the Japan Society of Aesthetic Plastic Surgery
· Member of the Society of Anti-aging Medicine for Women
· Member of the European College of Aesthetic Medicine and Surgery

Certifications and Accreditations:

· Certified Trainer and Instructor for Hyaluronic Acid Filler Injection by Galderma (Switzerland)
· Certified Specialist of Restylane and Macrolane
· Certified Specialist of Doublo Treatments
· Certified Specialist of Thermage Treatments
· Certified Specialist of Dr. Obagi's Cosmetics

Clinic Schedule:Tuesdays - Saturdays (Reservation required)

Introduction of our doctor

Neal Rouzier M.D

Dr. Rouzier is famous as an innovator and leader in the anti-ageing field and has been praised for his anti-aging and preventive medicine specialties. He has excellent credentials for curing thousands of patients by usung natural hormone replacement therapy. He has been contributing to state-of-the-art anti-aging medical care with great success through medical papers, academic meetings, clinical research, and various media. He is also popular as a public speaker and leader in his home country, the U.S.A.


Dr. Rouzier completed residency training in Family Practice and Emergency Medicine in UCLA (University of California, Los Angeles). He is a certified emergency physician and was Assistant Director of Queen of the Valley Hospital in West Covina for 15 years. In 1997, he became the Medical Director of the Preventive Medicine Clinic of the Desert/PMC (Palm Spring, California). He is a world-renowned expert in bioidentical hormone replacement therapy.

Polaris laser / Carbomed / Therma cool / Photofacial(IPL) / Collagen,Restylane,Humancollagen / Pore carbon laser / Dr's Chemical peeling (AHA,BHA,TCA) / Botox / Ingection (Lip augumentation,nose augummentation / Injections and infusions / Piercing / Laser suregery / Excessive sweating,Botox injection (Armpits,Palms) / Eczema,Atopic dermatitis / Keloid / Wart,Mole / Laser hair removal / Airbrush tanning / CET Thermotherapy / Endermologie /Ionization・ultrasound (Vitamin C,Hyarulonic acid) / Permanent for eyelashes / Mascara(Last3~4weeks) / Eyelash extension
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